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Smear test

Abnormal smear test: what does it mean?

An abnormal smear test does not mean you have cancer. It means that cells were found that look different than normal. Here you can read what it entails and what the next steps are.

If your general practitioner (GP) calls with the message that your smear test is abnormal, your first thought might be: 'Do I have cancer?' Let us reassure you immediately: an abnormal smear test does not mean you have cancer.

It means that cells have been found that look different than normal. In the vast majority of cases, this is caused by an HPV infection. In many women, these abnormalities recover spontaneously.

What is a smear test?

A smear test (also called cervical cytology or PAP test) is an examination in which cells are taken from the cervix. In the Netherlands, women between the ages of 30 and 60 are invited every 5 years for the cervical cancer screening program.

In 2018, 799,173 women were invited and 460,518 women participated in this screening. Since 2017, testing for HPV is done first, and only in the case of an HPV-positive result are the cells evaluated.

The PAP results explained

The cells from the smear test are evaluated and classified according to the PAP system. Below you can see what each result means:

Result Meaning Severity Next step
PAP 1 Normal No abnormalities Regular check-up in 5 years
PAP 2 Slight abnormality Usually inflammation Repeat smear test
PAP 3a1 Slight abnormalities Mild Often repeat or referral to gynecologist
PAP 3a2 Moderate abnormalities Mild-moderate Referral to gynecologist
PAP 3b More serious abnormalities Moderate-severe Referral to gynecologist
PAP 4 Possible carcinoma in situ Severe Treatment by gynecologist
PAP 5 Almost certainly cervical cancer Very severe Treatment by gynecologist

What is the next step?

Depending on your PAP result, your GP will refer you to the gynecologist. the examination at the gynecologist proceeds as follows:

1

Referral to the gynecologist

Your GP refers you based on the PAP result.

2

Colposcopy

The gynecologist examines the cervix with a special camera and stains the cells.

3

Biopsy

Small pieces of tissue are taken for laboratory examination.

4

CIN result

The biopsy gives a CIN classification indicating how deep the abnormalities are.

5

Treatment plan

Based on the CIN result, the gynecologist advises observation, follow-up, or treatment.

Veelgestelde vragen

How quickly should I see a gynecologist?
With a PAP 3a result, you don't need to panic; it is not an emergency. But do make an appointment as soon as possible. Usually, you will be seen within a few weeks. With a PAP 4 or 5 result, action is taken more quickly.
Can I just go on with my life with an abnormal smear test?
Yes, an abnormal smear test has no immediate consequences for your daily life. You can just work, play sports, and have sex. However, it is important to keep the follow-up appointment with the gynecologist.
Does my partner also have the HPV virus?
There is a high chance they do. HPV is very contagious and is transmitted through sexual contact. Men are often carriers without knowing it. This is no reason for blame. The virus is so common that it is almost inevitable.
Can an abnormal smear test become normal again on its own?
Yes, it certainly can. Especially with mild abnormalities (PAP 3a / CIN 1), the smear test results recover spontaneously in many cases. The immune system plays a key role in this.
How common is an abnormal smear test?
More common than you think. In the screening program, HPV is found in a significant percentage of participants, and a portion of those also have abnormal cells. You are definitely not alone.

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