Genetic testing: insight into your DNA
With a genetic analysis, we map out your genetic strengths and weaknesses. This allows us to tailor nutrition and supplements precisely to what your body needs.
Every person is genetically unique. Your DNA largely determines how efficiently your body processes vitamins, detoxifies toxins, regulates inflammation, and handles stress. With a genetic test, we map these processes so we can intervene specifically where your body needs extra support.
At HPV Health, we collaborate with Igene for the analysis of your genetic predisposition. We recommend the most comprehensive test, which consists of DNA analysis including a personalized treatment plan.
of the population has an MTHFR mutation. This affects the methylation cycle, in which vitamin B12 and folate play an important role.
What is tested?
The genetic analysis examines multiple genetic variants that affect your health. Below is an overview of the most important categories:
| Category | What is examined | Why it's relevant |
|---|---|---|
| Methylation | MTHFR and related genes, CH3 groups | Determines how well you process B12, folate, and homocysteine |
| CYP enzymes / Detoxification | Cytochrome P450 enzymes, phase I and II detoxification | Shows how efficiently your liver breaks down toxins, hormones, and medications |
| Inflammation sensitivity | Genes involved in inflammatory responses | Explains why some people react more strongly to infections or stress |
| Bone density | Genetic predisposition for osteoporosis | Early detection makes prevention possible |
| Stress sensitivity | Genes that regulate stress response | Helps in understanding your stress patterns and recovery capacity |
| Vitamin and iron requirements | Genetic variants that influence requirements | Prevents deficiencies through tailored supplementation |
| Fat metabolism | Genes involved in fat processing | Influence on weight and risk of cardiovascular disease |
MTHFR mutations and methylation
One of the most common genetic variants is the MTHFR mutation. Approximately 45% of the population has one or more variants of this gene. MTHFR is essential for the methylation cycle, the process by which CH3 groups (methyl groups) are attached to DNA, proteins, and other molecules.
The methylation cycle is involved in:
- The processing of vitamin B12 and folate
- The breakdown of homocysteine
- DNA repair and gene expression
- The production of neurotransmitters
- The detoxification of hormones and toxins
An MTHFR mutation can lead to impaired methylation, giving you a higher need for specific forms of B12 (methylcobalamine) and folate (methylfolate). Without targeted supplementation, this can contribute to fatigue, mood issues, and a weakened immune system.
Methylation is an important process in your body's cells where a methyl group is transferred to other molecules, such as proteins, amino acids, toxins, enzymes, and DNA. Through this coupling, the function of the substance in question changes, activating or regulating various biological processes. B12 and folic acid play an important role in this. Without proper methylation, the body can fall out of balance in many areas. The MTHFR gene converts folate or folic acid into the active form 5-MTHF. You can imagine that if you do not get enough folic acid and cannot properly convert it into the active form, it has an impact on your health!
DNA and methylation
Methylation is a central process in your body where SAMe (S-adenosylmethionine) acts as a universal methyl donor. SAMe is involved in the production and breakdown of neurotransmitters such as dopamine and adrenaline, the processing of estrogen, and the regulation of gene expression. When methylation is disrupted, it can affect all these processes simultaneously.
How does it work?
The genetic testing process
Application and collection
Based on our advice, you purchase a test kit with which you collect DNA material at home via a cheek swab. This is sent to the Igene laboratory.
Analysis by Igene
The laboratory analyzes your DNA for relevant genetic variants. This usually takes several weeks.
Personalized treatment plan
Based on the results, an analysis follows of many individual genes and their functions. This can be linked to the practitioner, who creates a comprehensive analysis.
Discussion and guidance
We discuss the results in detail during a consultation and translate the genetic data into a concrete plan with nutrition and supplements, tailored to your genetic weak points.
Why professional guidance?
Genetic tests produce complex data that can be misleading without expert interpretation. A gene variant is not the same as a disease: it is about predisposition and sensitivity. Proper interpretation requires knowledge of:
- The interaction between different gene variants
- The influence of lifestyle and environmental factors
- The interaction between supplements and genetic profiles
- The prioritization of interventions
At HPV Health, we ensure that the results are translated into a practical and achievable plan. You don't get a pile of data, but clear advice that you can apply immediately.
Costs
The most comprehensive genetic analysis via Igene, the DNA Health test, costs around €300,00. In addition to this test, Igene charges fees to activate the genes, around €175,00. This can only be initiated by the practitioner who analyzes the test. The costs of a comprehensive analysis, drawing up a treatment plan, and a meeting in which we go over everything, cost €275,00.
Curious about your genetic profile?
A genetic test offers lasting insight into your body. We would be happy to discuss whether a genetic analysis is useful in your situation.
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Is a genetic test useful for everyone?
How much does the genetic test cost?
What is the difference between this and a DNA test for ancestry?
Do I only have to do the test once?
How does the genetic test relate to the OligoScan?
Questions about your situation?
Feel free to get in touch for personal advice about your HPV diagnosis.
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